Wei-Hung’s paper entitled “Force-Dependent Extracellular Matrix Remodeling by Early-Stage Cancer Cells Alters Diffusion and Induces Carcinoma-Associated Fibroblasts” has been accepted to be published in Biomaterials . This project is a long time coming. We are pleased that it finally has come to a conclusion on the first day of the new decade. We are very excited to be able to share our finding with the biophysics community. Congratulations!
Wei-Hung’s Paper about Biophysical Characterization of the Tumor Microenvironment is Accepted
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Matt Wins Travel Award for 2020 Biophysical Society Annual Meeting
Matt is selected for the Travel Award to present his work on the cytoskeleton dynamics during extreme cell migration at the 2020 Biophysical Society Annual Meeting (https://www.biophysics.org/2020meeting#/) . Congratulations!
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Keva Wins the 2nd Place at the 5th Annual INBT Undergraduate Research Symposium Poster Competition
Keva presented her research work at the and was awarded as the 2nd place for her outstanding work. Each presenter was judged on criteria like the project’s impact on the scientific community and the depth of their presentation (see more at https://www.jhunewsletter.com/article/2019/11/inbt-hosts-symposium-for-undergrad-researchers) .
Keva excelled in explaining her work to the audience. We are very happy and proud of you, Keva. Congratulations!
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Keva wins Provost’s Undergraduate Research Award (PURA)
We are very pleased to learn that Keva has been selected to receive Provost’s Undergraduate Research Award (PURA) for 2019. Keva has been working on the project of extreme cell motility with Matt’s supervision. Her work is also selected to be presented at the annual ASCB meeting this December. Congratulations on the good job, Keva!
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Halloween 2019
This year we dressed as princesses for Halloween at the weekly group meeting. Everybody felt pretty and shiny and empowered. Go MOBsters!
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The iPSC-derived Cardiac Tissues Paper is Featured on World Heart Day
To bring awareness of cardiovascular disease, Wiley compiled a World Heart Day (September 29th) collection. Our paper “Mechanical Characterization of hiPSC‐Derived Cardiac Tissues for Quality Control” is featured in the collection. We are glad we are part of the efforts in innovative treatment for heart failures.
Figure: The fabrication steps of printing implantable cardiac tissues. a) hiPSC‐derived cardiomyocytes, endothelial cells, and fibroblasts are combined to form spheroids in U‐bottom, 96‐well plates. The spheroid is used as a basic building block for patch construction. b) Individual spheroids are picked up by the 3D bioprinting tip and transferred onto needle arrays to form the patch. c) After spheroids are fused together, the cardiac patch is decannulated and cultured under the needle‐free condition to allow maturation. Insets: a cardiac patch and a spheroid are shown in blue‐ and red‐framed images.
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End of Summer Group Lunch 2019
We had lunch after the group meeting to celebrate recent papers and the beginning of the Fall semester. More importantly, we bid goodbye to our amazing summer interns, Zheming, Zixian and Yuhan. They left us with fond memory of working with talented young scientists, and tons of good data! As we send off the summer with the summer interns back to their school, we wish the best for them and hope our paths will cross again soon!
Seungman’s Force Measurement Paper is Accepted
Seungman’s methods paper “Versatile and High-throughput Force Measurement Platform for Dorsal Cell Mechanics” is accepted. Seungman not only came up with the idea for the paper but also did a terrific job training our beloved former undergrad research assistant Ed, aka the second author of the paper. Missions well accomplished all around!
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Welcome Junjie
We welcome Junjie Chen to be the newest addition to the Lab of MOBS. Junjie double-majored in Biomedical Engineering and Anthropology during his undergraduate study at Purdue University. We hope you will enjoy and excel in Mechanical Engineering as well. We are very excited to have you on board, Junjie!
Wei-Hung’s Curvature-Sensing Paper is Accepted
Wei-Hung’s paper “cell-cell adhesion and myosin activity regulate cortical actin
assembly in mammary gland epithelium on concaved surface” is accepted to be published in Cells, a well-timed good news. It has been a long battle. Thanks for trooping on, Wei-Hung! And congratulations to all the authors. Special thanks are due to our wonderfully amazing collaborator Prof. Sung Hoon Kang – thanks for believing in a crazy idea – your blind faith in us finally pays off.
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